6-K: Report of foreign issuer [Rules 13a-16 and 15d-16]
Published on
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington. D.C. 20549
Form 6-K
REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR I5d-16
UNDER THE SECURITIES EXCHANGE ACT OF 1934
For the month of September, 2003
Novogen Limited
(Translation of registrant's name into English)
140 Wicks Road, North Ryde, NSW, 2113, Australia
(Address of principal executive office)
[Indicate by check mark whether the registrant files or will file
annual
reports under cover of Form 20-F or Form 40-F.
Form 20-F v Form 40-F
[Indicate by check mark whether the registrant by furnishing the
information contained in this Form is also thereby furnishing the
information to the Commission pursuant to Rule 12g3-2(b) under the
Securities Exchange Act of 1934. Yes No
[If "Yes" is marked, indicate below the file number assigned to the
registrant in connection with Rule 12g3-2 (b):
82- ________________ .1
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of
1934, the registrant has duly caused this report to be signed on
its behalf by the undersigned, thereunto duly authorized.
Novogen Limited
(Registrant)
Date 25 September, 2003 By Ronald Lea Erratt, Company secretary
Letter to Shareholders from the Managing Director
Dear Shareholders,
It is a pleasure to report the results for the financial year 2002/3.
Improved financial performance
Novogens accelerating achievements in research development and
clinical trials have been achieved within a strategy of cash control
and retention, and continuing improvement in our financial performance.
Our end of financial year results confirm that our achievements
have been reached within a firm and continuing commitment to
these stated objectives.
Phenoxodiol and Marshall Edwards Inc.
The anti-cancer drug that is most advanced along
the clinical pathway is phenoxodiol. This drug has been licensed
to our listed US subsidiary company Marshall Edwards Inc.(MEI).
Novogen makes phenoxodiol and Novogen personnel are contracted by
MEI to continue the management of the phenoxodiol program. Our
fortunes as they relate to phenoxodiol are very closely linked.
Novogen currently owns 95.1 percent of MEI. MEI also has certain
rights to take in on license, on commercial terms, any other
Novogen anti-cancer compound that enters into clinical trials.
Positive television coverage
Recent positive media exposure in the US and in Australia,
about our progress at the Yale University Medical Center, has
offered an insight into the potential of our entire drug development
and clinical trial programs. The news reports emanating from Yale
allow interested shareholders and future patients of our
anti-cancer program, the opportunity to glimpse the potential
opportunities at Novogen.
However two aspects about media exposure must be emphasised.
Firstly, the Company is unable to speak to the media or
shareholders about the results of trials in progress unless
the clinicians running the trials have publicly released their
findings. Secondly, the timing of the release of information
by the clinicians and institutions involved in the trials is
totally in their hands, and the Company cannot foreshadow when
those releases will be. Nevertheless, it is most encouraging
when the results are finally revealed and patients have clearly
benefited from their participation in the clinical program.
Announcements to shareholders
We have had a prolific schedule of announcements about our
developments and milestones during the last financial year.
These are best summarised by this chronological listing for
each of our main business and therapeutic area programs.
Corporate
(i) Novogen wins annual Australian Technology Showcase
award 10 September, 2002.
(ii) Novogen receives $A2.3 million royalty payment from
DuPont Protein Technologies 6 January, 2003.
Anti cancer
(i) Marshall Edwards, Inc. and the National Institutes
of Health join forces to study the anticancer drug,
phenoxodiol 24 July, 2002.
(ii) Marshall Edwards Inc. and Yale University School of
Medicinel to develop phenoxodiol for ovarian cancer
28 August, 2002.
(iii) Marshall Edwards Inc begins phase II trial for
phenoxodiol at Yale University School of Medicine for women
with ovarian cancer 10 December, 2002.
(iv) Yale researchers report phenoxodiol kills ovarian
cancer cells 1 April, 2003
(v) Skin cancer phase II trial approved for oral phenoxodiol
at Royal North Shore Hospital 8 April, 2003
(vi) Oncogene publishes phenoxodiol data 1 May, 2003
(vii) Yale researchers discover that phenoxodiol, combined
with small doses of chemotherapy, reduces ovarian cancer
tumour mass by 75 percent 2 June, 2003
Cardiovascular
(i) Novogens cardiovascular drug program outstanding
in first human clinical trial 9 September, 2002.
NV07
(i) New Human trial commences for Novogens dermatological
compound NV07a 13 June, 2002
(ii) Major new cosmetic opportunity, researchers discover
new mode of action for Novogen skin repair compound NV07a
18 September, 2002.
(iii) US patent issued to Novogen covering skin repair
compound NV07a 26 September, 2002.
(iv) Australian patent granted to Novogen covering its
skin repair compound NV07a 13 January, 2003.
Glycotex
(i) Novogen Group commences phase II trial for skin ulcer
repair 8 May, 2003
Consumer products
(i) Promensil produces significant cholesterol reduction
in women new study 17 June, 2002
(ii) Novogen granted US patent covering soy hypocotyl, a
natural source of isoflavones 16 January, 2003.
(iii) Novogen awarded US patent for isoflavones to treat
menopause and PMS 20 May, 2003
(iv) Novogen awarded US patent for isoflavones to treat
estrogen dependent disease 18 August, 2003
Biotechnology and stock market sentiment
This year has seen waves of mixed sentiments wash over the
biotechnology sector. This lack of continued support and
itinerant interest in technology focused businesses has left
some companies in a parlous financial condition. This is not
the case with Novogen and Marshall Edwards Inc, because we
have managed the business to ensure a viable financial
performance, whilst maintaining the momentum of our clinical
achievements.
This balanced and measured direction has ensured that our
R&D and clinical trials were able to continue to expand
and create the value for shareholders that is embodied in
our intellectual property portfolio.
This approach also enabled the group to raise over
US$10 million in an initial stock market placement when MEI
listed on the London Stock Exchange Alternative Investment
Market in the middle of 2002, and at a time when the sentiment
for the biotechnology sector as a whole was at its lowest.
In mid 2003 we also raised equity into our US company
Glycotex, Inc., to initiate clinical trials with our
topical wound healing product.
These were financially counter cyclical activities possible
because of our steady and constant progress across our programs.
The biotechnology sector, at this stage of development in
Australia in particular, has the potential for significant
capital growth, and the recent improvement in the investment
climate for the sector suggests that reinvestment and capital
growth will be the measures of success rather than conservative
competition with low growth albeit dividend paying established
industries.
The year ahead
Our advances in each of our programs and business areas
over the last year have established an exciting platform
for financial and scientific achievements in the coming year.
We enter 2003/4 with a solid cash position, and an improving
financial performance.
The enthusiasm, focus and talents of our staff and those of
our international collaborators are combining to achieve some
critical scientific and medical advances that have the potential
to rewrite the preferred treatment regimes for a number of
medical conditions.
Thank you for your support this year and we all
look forward to an exciting year of developments and
achievements in 2003/4.
Yours sincerely
Christopher Naughton
Managing Director
More information on the Company can be found at
www.novogen.com.
ISSUED FOR : NOVOGEN LIMITED
LISTINGS : ASX (CODE NRT), NASDAQ (CODE NVGN).
FOR FURTHER INFORMATION : CHRISTOPHER NAUGHTON,
MANAGING DIRECTOR, NOVOGEN LIMITED TEL +61 2 9878 0088
ISSUED BY : WESTBROOK COMMUNICATIONS CONTACT:
DAVID REID TEL +61 2 9231 0922 OR 61 417 217 157